One advantage of bupropion is that users begin taking the medication prior to quitting smoking, thereby priming their body to deal with the stress of quitting. Some smokers may lose their desire to smoke prior to their quit date or reduce the amount they smoke. Bupropion may be a good choice for people who prefer an alternative to nicotine replacement, or who have not succeeded on traditional nicotine replacement therapies. It is effective for both genders and has been shown to aide cessation in depressed patients. Heavily-addicted smokers may benefit from using bupropion along with a nicotine patch and/or a short-acting form of NRT (such as gum or lozenges). Weight gain is delayed while taking it, not after stopping. Bupropion is generally well tolerated in persons with cardiovascular disease.
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