Some people who use lozenges experience soreness in the gums and teeth, irritated throat tissue, hiccups, or heartburn/indigestion. These symptoms usually become more manageable over time.
Medical review: Nathan Cobb, MD, September 25, 2017
Fiore MC, Jaén CR, Baker TB, et al. Treating Tobacco Use and Dependence: 2008 Update. Clinical Practice Guideline. Rockville, MD: U.S. Department of Health and Human Services. Public Health Service. May 2008.